ORTHO EVRA (norelgestromin/ethinyl estradiol transdermal system)
About Evra
Important Safety Information
Using Ortho Evra
How To Get the Patch
When To Start
When Protection Begins
Applying The Patch
Switching From Another Birth Control Method
Birth Control After Pregnancy
What To Expect
Are There Any Side Effects?
Want To Change Your Patch Day?
Forget To Change Your Patch?
Want To Become Pregnant?
Patient-Doctor Discussion Guide
Frequently Asked Questions
Birth Control Info
NewsRoom
For Prescribers
Full US Prescribing Info
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What can I expect while using the Patch?
Because every woman is unique, it's almost impossible to predict how your body will respond to ORTHO EVRA. Some women notice minor changes while others notice no changes at all.

Find out what you can expect when you start using the birth control patch.

First 3 Months
3 Months and Beyond
Smart Strategies

First 3 Months

If you experience any side effects, they're most likely to occur in the first 1 to 3 cycles and may disappear. Excluding possible irritation at your patch site, the types of common side effects reported in clinical trials were similar to other hormonal contraceptives.

Most women in these trials described any side effects as mild to moderate and very few (approximately 2%) stopped using the Patch because of them. Some women experienced breast discomfort, headache, nausea, painful periods, upper respiratory infection, or skin irritation where the Patch was applied.

In the first 3 months, you may experience these temporary side effects:
  • Breast discomfort: Tender or sore breasts are common premenstrual symptoms, and may occur when you first begin using the Patch. Approximately 8 out of 10 women in clinical trials who reported breast discomfort described the side
    effect as mild to moderate. Most women found this
    decreased with each cycle, and only 1% stopped using ORTHO EVRA because of it. Breast tenderness typically decreases by the third month.
  • Breakthrough bleeding and spotting: Breakthrough bleeding and spotting are side effects that may occur when you use hormonal contraceptives. In clinical trials, very few women (3.7%) experienced bleeding while using
    ORTHO EVRA in their first cycle. Most women's menstrual periods started on the fourth day of their patch-free week, lasting 5 to 6 days. There was a low discontinuation rate due to bleeding (0.5%) in clinical trials. Most women started withdrawal bleeding on the fourth day of the drug-free
    interval. The median duration of withdrawal bleeding was
    5 to 6 days. Including withdrawal flow and breakthrough bleeding and/or spotting, on average 26% of women per
    cycle had 7 or more days of bleeding and/or spotting.
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3 Months and Beyond

When you're in your third or fourth month, side effects should no longer be
a frequent annoyance. If you're one of the few women who experienced common side effects, such as breast symptoms or breakthrough bleeding and spotting, relief may be in sight.
  • Breast discomfort: By your third month on ORTHO EVRA, breast discomfort is unlikely to be an issue. Clinical studies showed that most breast discomfort happens in the first
    2 months of patch use. Remember, some breast discomfort may happen right before your period, and that's completely normal.
  • Breakthrough bleeding and spotting: Irregular bleeding that varies from slight staining between periods to breakthrough
    bleeding with a flow similar to your regular period is
    temporary and not a sign of any serious problem. It's important to continue using your patches on schedule, changing them regularly on your designated Patch Change Day. If you're sticking to your schedule and bleeding
    continues for more than a few days or lasts for more than a few cycles, talk to your healthcare professional.
  • No period: If you're sure you've been using ORTHO EVRA correctly and you don't get your period for 2 consecutive cycles-there's a chance you may be pregnant. You also could be one of the very few women on ORTHO EVRA
    (0.1% in clinical trials) who experience no period at all (a condition called amenorrhea). Call your healthcare professional if you suspect either condition.
  • Skin irritation: At this point, skin irritation around your patch should be minor. If redness, irritation or itchiness continues,
    simply remove your patch, discard it, and replace it with a
    new one in a new location until your next Patch Change Day. Changing patch locations will help avoid further skin
    irritation.
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Click here to learn more about ORTHO EVRA benefits, precautions, side effects, warnings, and other important patch information.

If you are uncomfortable with any side effects that you may experience, make a note of the occurrence and discuss it with your doctor or other healthcare professional.

SMART STRATEGIES

ORTHO EVRA occasionally causes skin irritation, redness or rash at the placement site. Most often this can be avoided by simply selecting a new patch site each week.
  • To make sure ORTHO EVRA sticks properly to your skin,
    don't use creams, oils, powder, or makeup where you intend to put your patch or near a patch you already are
    wearing - this can cause it to come loose.
  • If mild irritation develops during use, apply a new patch to a new location. Then start another new patch on your regular Patch Change Day. Remember: only wear one patch at a
    time!
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